Fitness

What are BCAAs?

BCAAs are three essential amino acids sold as a muscle-building shortcut. Here's what the research supports, what it doesn't, and why whole protein works better.

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You've probably seen "BCAA" on the back of a gym supplement or heard it in the locker room. BCAA stands for branched-chain amino acids, and they're marketed as a shortcut to muscle growth and faster recovery. Here's what they are, what the research actually supports, and why whole protein usually does the job better.

What are BCAAs?

BCAAs are three amino acids: leucine, isoleucine and valine. They're named for the branched shape of their chemical structure. All three are among the nine essential amino acids, which your body can't make and must get from food.

Amino acids are the building blocks of protein. When you eat protein, your body breaks it into amino acids and uses them to build and repair tissue, or burns them for energy. Leucine in particular acts as a signal: amino acids, and especially leucine, help switch on the cellular pathways that control protein synthesis.

Do BCAA supplements build muscle?

Not on their own. Building new muscle protein takes all nine essential amino acids, not just three. A review of the evidence found no human studies showing that oral BCAAs alone increase muscle protein synthesis, and concluded that the claim that BCAA supplements produce an anabolic response is unwarranted. When only BCAAs are available, the other essential amino acids have to come from breaking down existing muscle protein.

That's why complete protein is the better tool. Protein supplementation during resistance training increased strength and muscle size in a meta-analysis of 49 studies, and complete proteins naturally contain plenty of BCAAs alongside the other essential amino acids.

Do BCAAs reduce muscle soreness?

This is where BCAAs look most promising. A 2024 meta-analysis of 18 trials found that BCAA supplementation reduced delayed-onset muscle soreness 24 to 96 hours after muscle-damaging exercise, with larger effects at higher doses and longer supplementation. Another meta-analysis found benefits mainly in trained people at low to moderate doses, but noted that studies varied too much to say whether BCAAs help untrained people.

So BCAAs may take the edge off soreness after a hard session. They're not a substitute for enough total protein, sleep and sensible training progression.

Do BCAAs reduce fatigue or improve performance?

The idea is that BCAAs compete with tryptophan, the building block of serotonin, and so might delay "central" fatigue during long exercise. It's an interesting theory, but several well-controlled laboratory studies have not shown a benefit for exercise capacity or performance in temperate conditions.

Are there other benefits?

Older versions of this article listed liver, kidney, heart, diabetes and sleep benefits. The evidence doesn't support those as reasons to take BCAA supplements, and one of them points the other way: higher blood levels of BCAAs are associated with obesity, worse metabolic health and future insulin resistance or type 2 diabetes. Researchers are still working out what that association means, but it's a good reason not to treat BCAA supplements as a health tonic. If you have liver or kidney disease, talk to your doctor before taking amino acid supplements.

How do you get BCAAs from food?

Any protein-rich food supplies BCAAs. Animal sources include meat, fish, dairy and eggs. Plant sources include beans, lentils, soy, quinoa, nuts and seeds. Plant proteins vary in their amino acid makeup, with leucine content ranging widely between plant protein isolates, which is one reason blends of complementary plant proteins work well.

If you'd like a convenient source, So Lean & So Clean provides 23g of complete organic plant protein per serving from pea and rice, so you get all nine essential amino acids, BCAAs included, with no added sugar. For more on mixing sources, read why eating a variety of protein sources matters, and for targets, how much protein you need.

Frequently asked questions

What does BCAA stand for?

Branched-chain amino acids: leucine, isoleucine and valine. They are essential amino acids, so they must come from food.

Do BCAAs help build muscle?

Not on their own. Building muscle protein needs all nine essential amino acids, and a review found no human evidence that BCAAs alone increase muscle protein synthesis. Complete protein is the better choice.

Do BCAAs help with muscle soreness?

They may. Meta-analyses found BCAA supplements reduced delayed-onset muscle soreness after muscle-damaging exercise, especially in trained people.

Do I need BCAAs if I eat enough protein?

Usually not. Protein-rich foods and complete protein powders already contain BCAAs along with the other essential amino acids.

References

  1. MedlinePlus. Amino acids. U.S. National Library of Medicine. https://medlineplus.gov/ency/article/002222.htm
  2. Kimball SR, et al. Amino acids as regulators of gene expression. Nutr Metab (Lond). 2004;1(1):3. https://pubmed.ncbi.nlm.nih.gov/15507151/
  3. Wolfe RR. Branched-chain amino acids and muscle protein synthesis in humans: myth or reality? J Int Soc Sports Nutr. 2017;14:30. https://pubmed.ncbi.nlm.nih.gov/28852372/
  4. Morton RW, et al. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. Br J Sports Med. 2018;52(6):376-384. https://pubmed.ncbi.nlm.nih.gov/28698222/
  5. Salem A, et al. Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression. Sports Med Open. 2024;10(1):42. https://pubmed.ncbi.nlm.nih.gov/38625669/
  6. Weber MG, et al. The use of BCAA to decrease delayed-onset muscle soreness after a single bout of exercise: a systematic review and meta-analysis. Amino Acids. 2021;53(11):1663-1678. https://pubmed.ncbi.nlm.nih.gov/34669012/
  7. Meeusen R, et al. The brain and fatigue: new opportunities for nutritional interventions? J Sports Sci. 2006;24(7):773-82. https://pubmed.ncbi.nlm.nih.gov/16766505/
  8. Lynch CJ, et al. Branched-chain amino acids in metabolic signalling and insulin resistance. Nat Rev Endocrinol. 2014;10(12):723-36. https://pubmed.ncbi.nlm.nih.gov/25287287/
  9. Gorissen SHM, et al. Protein content and amino acid composition of commercially available plant-based protein isolates. Amino Acids. 2018;50(12):1685-1695. https://pubmed.ncbi.nlm.nih.gov/30167963/