Grape seeds are full of proanthocyanidins, potent antioxidant molecules. Studies have shown that grape seed extract may act as a stronger antioxidant than Vitamins C and E. Research suggests that the anti-inflammatory action of grape seed extract may be mediated through a reduction in NF-kB, which governs the body's inflammatory response. One study showed that grape seed extract may reduce oxidative damage in the DNA of skin cells exposed to UVB.