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Natural GLP-1 Support

$74.99
$74.99
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Natural GLP-1 Support

GLP-1 Up

4 Patented Ingredients Eriomin® & Morosil® Cravings & Glucose Support
Ships within 1 business day. Estimate only. Business days, excluding weekends and holidays.
60-Day Money-back Guarantee

We stand by the quality of our products as the best in the industry! So much so, that if you don't love your product - for any reason - we'll refund you in full within 60 days of your first purchase.

HSA/FSA eligible Save an average of 30% Learn more

Pay with HSA/FSA and save

Save an average of 30% when you pay with pre-tax HSA/FSA funds. No added costs.

  1. At checkout, pay with Truemed If you’re logged into Shop Pay, select "Pay another way" or "More payment options" to find Truemed.
  2. Complete health survey and pay Take a brief health survey, then pay with your HSA/FSA card or a personal credit or debit card.
  3. Receive Letter of Medical Necessity (LMN) A licensed provider reviews your answers. Qualified customers get an LMN for HSA/FSA documentation. And if you don’t qualify, your card doesn’t get charged.

Truemed is for qualified customers. HSA/FSA tax savings vary. Learn more at truemed.com/disclosures

Benefits
  • Supports your body’s natural GLP-1 production†*: Eriomin® has been clinically shown to support up to a 22% increase in GLP-1, a key hormone that helps regulate appetite, insulin, and energy balance.†
  • Promotes a healthy blood sugar response†*: Reducose® slows down the breakdown of carbs to reduce post-meal glucose spikes by up to 40%, while Feiolix® supports insulin sensitivity and glucose metabolism.†
  • Supports a gut environment where GLP-1 thrives†*: Eriomin® and Feiolix® promote a healthy metabolic environment by supporting gut health and maintaining balanced oxidative stress and inflammation responses.†
  • Targets fat — not muscle†*: Morosil® has been shown to reduce waist and hip circumference and support healthy body composition when paired with a balanced diet and exercise.†

*Benefits as shown are reported in ingredient-specific studies
Ingredients

OraGlucose Guard™ supports natural GLP-1 production, slower carb digestion, and healthy insulin sensitivity.

Feijoa Powder (Acca sellowiana)(Fruit) Feiolix®, Lemon Flavonoids Extract (Citrus limon)(Fruit)(*70% Eriocitrin) Eriomin®, Mulberry Leaf Extract (Morus alba) (5% 1-Deoxynojirimycin (DNJ)) Reducose®


OraBurn™ turns up the heat, helping your body burn fat instead of storing it.

Sicilian Red Orange Extract (Citrus Sinensis L.Osbeck Moro Variety)(fruit) Morosil®, Ceylon Cinnamon (Cinnamomum verum)(bark)


Your metabolism dream team is all safely contained within a simple vegetarian capsule.

Supplement Facts
How to Use

Take 2 capsules daily around 10 minutes before starting your largest or most carb-heavy meal of the day - that’s usually lunch for most folks.

Many people begin to feel the effects - like fewer crashes or better portion control, within the first week. For full metabolic benefits (like changes in fasting glucose, waist circumference, or body composition†), we recommend taking GLP-1 Up consistently for at least 8–12 weeks alongside a healthy diet and exercise routine.

Don't like capsules? Try this trick!

Put 1 or 2 capsules in your mouth, take a sip of water, and then tilt your head forward before swallowing. This creates an air pocket in your mouth, making the capsules easier to swallow. Or break them open and mix into a smoothie!
Quality & Safety Testing

We don't think you should have to take a supplement company's word for it. So every batch we make is tested by an accredited third-party lab for potency, purity and safety. Our Five Nation Standard draws on rigorous requirements from Switzerland, Japan, Germany, New Zealand and the United States. Then we publish the Certificate of Analysis, so you can see exactly what we tested and exactly what we found.
Manufacturing

Made in California, U.S.A. in a cGMP-certified facility from local and globally-sourced ingredients.
  • Clinically-studied ingredients
  • Third-party tested
  • Non-GMO
  • Plant-based

Performance Enhancing Plants™

Powered by plants, not synthetic pharmaceuticals

Natural GLP-1 Support
  • Eriomin® Eriocitrin

    Eriomin® Eriocitrin

    Citrus limon

    Sourced from lemon fruit flavonoids, Eriomin® supports natural GLP-1 production by maintaining oxidative balance and healthy gut signaling.† Clinically shown to increase GLP-1 levels by up to 22% while supporting insulin sensitivity.†

  • Reducose® Mulberry Leaf Extract

    Reducose® Mulberry Leaf Extract

    Morus alba

    This white mulberry leaf extract mimics the shape of sugars and starches, distracting your digestive enzymes so up to 40% of carbohydrates may pass through the GI track undigested, leading to a lower blood sugar response.†

  • Morosil® Blood Orange Extract

    Morosil® Blood Orange Extract

    Citrus sinensis

    Sourced from Moro blood oranges grown in volcanic Sicilian soil and clinically studied in humans to support healthy body composition.† In a 12-week clinical trial, participants lost weight and saw a reduction in waist/hips measurements.†

Feel the difference

Other brands
Supports your body’s natural GLP-1 production†
No known side effects
Targets multiple pathways: blood sugar, appetite, energy, fat metabolism†
Includes 4 patented, clinically studied ingredients
Easy to take capsules
Under $80 a month
No synthetic hormones
The smarter way to support metabolism

The smarter way to support metabolism

  • 4 patented, clinically studied botanicals for targeted metabolic support†
  • Supports natural GLP-1 production for appetite and energy balance†
  • Supports a healthy post-meal glucose and insulin response†
  • Promotes healthy fat metabolism while preserving lean muscle†

We test every batch. Then we publish the results.

We don't think you should have to take a supplement company's word for it. So every batch we make is tested by an accredited third-party lab for potency, purity and safety. Our Five Nation Standard draws on rigorous requirements from Switzerland, Japan, Germany, New Zealand and the United States. Then we publish the Certificate of Analysis, so you can see exactly what we tested and exactly what we found.

See the Certificates of AnalysisHow we test
Tested for100%
potency
Tested for70
pesticides
Tested for28
residual solvents
Tested for8
allergens
Tested for6
microbials
Tested for4
heavy metals

Frequently Asked

When will I start to feel a difference?
  • Week 1: Feel it fast - Reducose® starts working within the first hour of your first serving, and has been shown to help post-meal blood sugar and insulin spikes by up to 40% — supporting better energy and fewer cravings from the jump.†
  • Week 4: Body composition shifts begin - Morosil®, when paired with a balanced diet and exercise, begins supporting early changes in body composition.† Eriomin® helps improve insulin sensitivity and supports healthier fasting glucose for more consistent energy.†
  • Week 8: Deeper metabolic support - Reducose® continues to moderate glucose response and appetite.† Morosil® sustains healthy fat metabolism, while Eriomin® supports natural GLP-1 production and gut balance for stronger overall metabolic function.†
  • Week 12: Peak results begin - Eriomin® has been shown to increase natural GLP-1 levels by up to 22%, optimizing satiety, insulin activity, and energy balance.† Morosil® and Feiolix® work in tandem to support healthy body composition, lipid levels, and long-term metabolic stability.†

In combination with healthy diet and exercise. GLP-1 Up is not a weight loss supplement. The product is formulated to support healthy weight management.†

What is GLP-1 and why does it matter?

GLP-1 (short for glucagon-like peptide-1) is a hormone your gut makes when you eat. It tells your brain you're full, keeps blood sugar steady, and helps you metabolize fat more efficiently. In other words: it’s your body’s built-in metabolic multitasker - and giving it a boost can help you feel more energized, less snacky, and better balanced overall.

Who is this product for?

GLP-1 Up is designed for adults seeking natural support for appetite regulation, post-meal energy, blood sugar balance, and healthy body composition. It’s ideal for people interested in GLP-1 benefits but looking for a plant-based, non-pharmaceutical approach.

Who is this product not for?

GLP-1 Up isn’t for kids, anyone with a citrus allergy, or people currently on GLP-1 meds (unless your doctor gives it a thumbs-up). As always, check with your doctor if you're managing a medical condition or taking medications that affect blood sugar or digestion.

How is this different from GLP-1 medications (i.e. semaglutide injections)?

Pharmaceutical GLP-1s flood your system with synthetic hormones to override your natural signals - which can lead to nausea, fatigue, bloating, or other less-than-fun side effects.

GLP-1 Up works with your body, not against it. It's clinically studied plant extracts help with natural GLP-1 production by supporting your body response to oxidative stress and inflammation.†

Can I take this while pregnant or breastfeeding?

We don’t recommend it. The ingredients haven’t been studied in these populations, so it’s best to wait. When in doubt, please ask your doctor.

Will this make me lose weight?

GLP-1 Up is not a weight loss drug. It supports your body’s natural GLP-1 pathways, which can help with satiety, cravings, and metabolic balance - all of which can absolutely support your goals when paired with healthy habits.†

Natural GLP-1 Support

Overall rating: 4.2923975 / 5 from 171 reviews.

AI Generated Review Summary

Natural GLP-1 Support aids in regulating appetite and energy levels. Users report improved focus and a reduction in cravings. Some users have experienced increased energy and a positive initial feeling, but results vary regarding weight loss and overall effectiveness.

Summary topics

  • Cravings Reduction (9%): Customers raved about Ora's Natural GLP-1 Support, praising its ability to reduce cravings.
  • Appetite Control (5%): Customers loved the GLP-1 supplement for its ability to curb appetite and improve energy.
  • Energy Levels (6%): It was highlighted by customers that they generally have more energy and are better able to focus on the task before them.
  • Initial Feeling (4%): It was observed by customers that they love this and feel amazing after taking this product for the first time.
  • Weight Management (12%): Customers have mixed opinions about the weight-loss aid, with some experiencing quick weight loss and others not seeing any change.

Review topics: ["weight","feel","improvement","issues","results","effects","energy","cravings","sugar","bottle","recommend","meal","stomach","dose","benefits","appetite","ingredients","impact","works","see","glp-1","sleep","protein","food","carb","process","belly","supplement","exercise","win"].

Review highlights

  • "My energy throughout the day is better and my side effects seem calmer" — Emily L.
  • "So far feel more energy and less cravings." — Lourdes H.
  • "I’m looking forward to seeing results of less bloating and possibly less weight as I go on using this product." — Kassandra H.

Reviews

Natural GLP-1 Support

"I’ve been on Natural GLP-1 Support for about a month and I’ve noticed it’s curbed my post-dinner cravings. I eat healthy in moderation and exercise regularly (one hour of cardio 5 days a week and strength training 3 to 4 days a week) but perimenopause has caused my weight to slowly creep up and nothing I do seems to make a difference. On the Natural GLP-1 Support, I’ve lost a couple of pounds already."

— Michelle O. (5/5)

large pill, but doable!

"It's a large pill, and I find it too hard to take as-is. However, the gel cap is easy to break open and the powder inside isn't totally unpleasant (I taste cinnamon and a slightly sour note). I find it easy to take when I mix it with a spoonful of water."

— Elle L. (4/5)

GLP-1 Is a game changer!

"I honestly love all of the Ora products, and I use quite a few of them. The GLP-1 has been a game changer. I have been taking this for a couple of months now and I see changes in my body. They are small, slow and steady, but working nonetheless. I feel positive about my progress."

— Kathleen G. (5/5)

2 months in

"I have been taking the GLP1 for almost 2 months. I have noticed a decrease in appetite and increased feeling of fullness after meals. I am still waiting to see a drop in clothing size. Will have to keep you posted ."

— Perl A. (4/5)

My energy throughout the day

"My energy throughout the day is better and my side effects seem calmer"

— Emily L. (5/5)

I am hopeful

"I had to stop two weeks in because I went away and forgot to bring it, but I feel better in myself and that means something"

— Mary F. (4/5)

Very good ,helps to reduce

"Very good ,helps to reduce cravings"

— Svetlana A. (5/5)

This product lives up to

"This product lives up to it's name! Highly effective and sustainable with a healthy lifestyle. I was diagnosed pre-diabetic and seen a reduction in my A1C numbers and weight over the six months or so. Definitely would recommend this to get and stay on track."

— Lynette B. (5/5)

Great

"I love everything about ora."

— Rochelle B. (5/5)

it does suppress my appetite

"it does suppress my appetite and I like the all natural ingredients"

— Jennifer G. (4/5)

Q&A

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